DMac
15th September 2010, 12:37 PM
Platinum and light together fight cancer (http://www.physorg.com/news203681015.html)
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(PhysOrg.com) -- Researchers continue to search for cancer treatments that effectively destroy tumor cells while protecting surrounding healthy tissue and the body. One intriguing approach involves photoactivated drugs: an inactive precursor would be administered, then the diseased tissue could be irradiated to convert the drug into its cytotoxic form locally.
Peter J. Sadler and his co-workers at the Universities of Warwick and Edinburgh, as well as the Ninewells Hospital in Dundee, have developed a new platinum complex that is suitable for this approach. As the British researchers report in the journal Angewandte Chemie, this new drug was demonstrably superior to conventional cisplatin.
snip
(PhysOrg.com) -- Researchers continue to search for cancer treatments that effectively destroy tumor cells while protecting surrounding healthy tissue and the body. One intriguing approach involves photoactivated drugs: an inactive precursor would be administered, then the diseased tissue could be irradiated to convert the drug into its cytotoxic form locally.
Peter J. Sadler and his co-workers at the Universities of Warwick and Edinburgh, as well as the Ninewells Hospital in Dundee, have developed a new platinum complex that is suitable for this approach. As the British researchers report in the journal Angewandte Chemie, this new drug was demonstrably superior to conventional cisplatin.